2-tosylbenzoic acid

Base Information

• Chemical Name: 2-tosylbenzoic acid
• CAS No.: 860699-53-2
• Molecular Formula: C₁₄H₁₂O₄S
• Molecular Weight: 276.313
• Mol file: 860699-53-2.mol

Synonyms:2-tosylbenzoic acid

Chemical Property of 2-tosylbenzoic acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-Tosylbenzoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-tosylbenzoic acid

There total 8 articles about 2-tosylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(toluene-4-sulfonyl)benzaldehyde (171503-27-8) → 2-tosylbenzoic acid (860699-53-2)

Guidance literature:

With sodium chlorite; potassium dihydrogen orthophosphite; water; In tetrahydrofuran; tert-butyl alcohol; at 20 ℃; for 15h;

Reference yield: 80.0%

C24H20N2O3S → 2-tosylbenzoic acid (860699-53-2)

Guidance literature:

With sodium hydroxide; In ethanol; at 130 ℃; for 24h;

DOI:10.1039/c5cc00202h

Reference yield:

→ 2-tosylbenzoic acid (860699-53-2)

Guidance literature:

With water; copper; at 125 - 135 ℃;

upstream raw materials:

n-butyllithium

diethyl ether

phenyltolylsulfone

N-quinolin-8-yl-benzamide

Refernces

• 1、 Liu, Jidan,Yu, Lin,Zhuang, Shaobo,Gui, Qingwen,Chen, Xiang,Wang, Wenduo,Tan, Ze. "Copper-mediated ortho C-H sulfonylation of benzoic acid derivatives with sodium sulfinates". . p. 6418 - 6421. Retrieved 2015/04/14.