Technology Process of C26H19FN4O3
There total 7 articles about C26H19FN4O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; ammonium chloride; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / tetrahydrofuran / 16 h / 20 °C
2.1: 7 h / 105 °C / Inert atmosphere
3.1: zinc; ammonium chloride / tetrahydrofuran; methanol / 2 h / 20 °C
4.1: hydrogenchloride / toluene; 1,4-dioxane / 16 h / 20 °C
4.2: pH 10
4.3: 3.5 h / 110 °C
5.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 1 h / 20 °C
5.2: pH 5
6.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; 4-methyl-morpholine; ammonium chloride / N,N-dimethyl-formamide / 1 h / 20 °C
With
4-methyl-morpholine; hydrogenchloride; lithium hydroxide monohydrate; water; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; ammonium chloride; N-ethyl-N,N-diisopropylamine; zinc;
In
tetrahydrofuran; 1,4-dioxane; methanol; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / tetrahydrofuran / 16 h / 20 °C
2.1: 7 h / 105 °C / Inert atmosphere
3.1: zinc; ammonium chloride / tetrahydrofuran; methanol / 2 h / 20 °C
4.1: hydrogenchloride / toluene; 1,4-dioxane / 16 h / 20 °C
4.2: pH 10
4.3: 3.5 h / 110 °C
5.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 1 h / 20 °C
5.2: pH 5
6.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; 4-methyl-morpholine; ammonium chloride / N,N-dimethyl-formamide / 1 h / 20 °C
With
4-methyl-morpholine; hydrogenchloride; lithium hydroxide monohydrate; water; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; ammonium chloride; N-ethyl-N,N-diisopropylamine; zinc;
In
tetrahydrofuran; 1,4-dioxane; methanol; N,N-dimethyl-formamide; toluene;