Rhodanine, 5-(cyclohexylmethylene)-

Base Information

• Chemical Name: Rhodanine, 5-(cyclohexylmethylene)-
• CAS No.: 73855-57-9
• Molecular Formula: C₁₀H₁₃NOS₂
• Molecular Weight: 227.351
• Mol file: 73855-57-9.mol

Synonyms:5-Hexahydrobenzylidenerhodanine;Rhodanine, 5-(cyclohexylmethylene)-;5-Hexahydrobenzylidene-4-oxo-2-thionothiazolidine;73855-57-9;C10-H13-N-O-S2;4-Thiazolidinone, 5-(cyclohexylmethylene)-2-thioxo-;SCHEMBL18102966;LS-143584

Chemical Property of Rhodanine, 5-(cyclohexylmethylene)-

Chemical Property:

• Density: 1.3g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 227.04385639
• Heavy Atom Count: 14
• Complexity: 293

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(CC1)C=C2C(=O)NC(=S)S2
• Isomeric SMILES: C1CCC(CC1)/C=C/2\C(=O)NC(=S)S2

Technology Process of Rhodanine, 5-(cyclohexylmethylene)-

There total 2 articles about Rhodanine, 5-(cyclohexylmethylene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

2-thioxo-4-thiazolidinone (141-84-4) + cyclohexanecarbaldehyde (2043-61-0) → (5Z)-5-(cyclohexylmethylene)-2-thioxothiazolidin-4-one (73855-57-9)

Guidance literature:

With ammonium acetate; In toluene; at 160 ℃; for 0.0833333h; Microwave irradiation;

DOI:10.1021/jm201243p

Reference yield:

→ (5Z)-5-(cyclohexylmethylene)-2-thioxothiazolidin-4-one (73855-57-9)

Guidance literature:

upstream raw materials:

2-thioxo-4-thiazolidinone

cyclohexanecarbaldehyde