N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

Base Information

Chemical Name:N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide
CAS No.:183146-46-5
Molecular Formula:C₂₀H₂₄N₄O₅
Molecular Weight:400.434
Hs Code.:

Synonyms:N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

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Chemical Property of N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

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Technology Process of N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

There total 5 articles about N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

: 54-96-6
3,4-diaminopyridine

: 3-(3-Isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzoyl chloride

: 183146-46-5
N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

: (+/-)-di-N,N'-(pyridin-3,4-diyl)-3-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxyl]-4-methoxybenzamide

Guidance literature:: With pyridine; triethylamine; In chloroform; for 36h; Ambient temperature;

Reference yield:

: 6702-50-7
3-hydroxy-4-methoxybenzoate

: 183146-46-5
N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) NaH / 1.) DMSO, 1 h, 2.) DMSO, 50 deg C, 20 h

2: 80 percent / LiCl / toluene / 72 h / 110 °C

3: 62 percent / 33percent aq. KOH / methanol / 3 h / 45 °C

4: SOCl₂ / benzene / 4 h / Heating

5: 46 percent / pyridine, Et₃N / CHCl₃ / 36 h / Ambient temperature

With pyridine; potassium hydroxide; thionyl chloride; sodium hydride; triethylamine; lithium chloride; In methanol; chloroform; toluene; benzene;

Reference yield:

: 183146-43-2
4-Methoxy-3-oxiranylmethoxy-benzoic acid methyl ester

: 183146-46-5
N-(3-Amino-pyridin-4-yl)-3-(3-isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-4-methoxy-benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / LiCl / toluene / 72 h / 110 °C

2: 62 percent / 33percent aq. KOH / methanol / 3 h / 45 °C

3: SOCl₂ / benzene / 4 h / Heating

4: 46 percent / pyridine, Et₃N / CHCl₃ / 36 h / Ambient temperature

With pyridine; potassium hydroxide; thionyl chloride; triethylamine; lithium chloride; In methanol; chloroform; toluene; benzene;