Technology Process of 3-(2-carboxybenzylthio)benzyl bromide
There total 7 articles about 3-(2-carboxybenzylthio)benzyl bromide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen bromide;
In
sulfolane;
at 15 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium aluminum hydride / tetrahydrofuran / 1 h
2: dimethylformamide; H2O / 0.33 h / Ambient temperature
3: 78.4 percent / sodium hydroxide; HCl / methanol; H2O / 1 h / Heating
4: 92 percent / dry hydrogen bromide / tetrahydrothiophene 1,1-dioxide / 3 h / 15 °C
With
hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; hydrogen bromide;
In
tetrahydrofuran; sulfolane; methanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85.6 percent / chlorosulfonic acid / 2 h / 120 - 125 °C
2: lithium aluminum hydride / tetrahydrofuran / 1 h
3: dimethylformamide; H2O / 0.33 h / Ambient temperature
4: 78.4 percent / sodium hydroxide; HCl / methanol; H2O / 1 h / Heating
5: 92 percent / dry hydrogen bromide / tetrahydrothiophene 1,1-dioxide / 3 h / 15 °C
With
hydrogenchloride; chlorosulfonic acid; sodium hydroxide; lithium aluminium tetrahydride; hydrogen bromide;
In
tetrahydrofuran; sulfolane; methanol; water; N,N-dimethyl-formamide;
