Dimethyl 2,3-dichlorosuccinate

Base Information

• Chemical Name: Dimethyl 2,3-dichlorosuccinate
• CAS No.: 62173-55-1
• Molecular Formula: C6H8Cl2O4
• Molecular Weight: 215.033
• Hs Code.: 2917190090
• European Community (EC) Number: 263-446-7
• NSC Number: 7191
• DSSTox Substance ID: DTXSID30886475
• Nikkaji Number: J90.555K
• Mol file: 62173-55-1.mol

Synonyms:Dimethyl 2,3-dichlorosuccinate;62173-55-1;dimethyl 2,3-dichlorobutanedioate;EINECS 263-446-7;TL 126;Butanedioic acid, 2,3-dichloro-, dimethyl ester;Butanedioic acid, 2,3-dichloro-, 1,4-dimethyl ester;Succinic acid, alpha,alpha'-dichloro-, dimethyl ester;C6H8Cl2O4;UNII-JU5J5943SE;JU5J5943SE;SCHEMBL2864267;DTXSID30886475;NSC7191;NSC 7191;NSC-7191;TL-126;Dimethyl 2,3-dichlorosuccinate, AldrichCPR;LS-147418;Butanedioic acid,3-dichloro-, dimethyl ester;FT-0640813

Chemical Property of Dimethyl 2,3-dichlorosuccinate

Chemical Property:

• Vapor Pressure: 0.0178mmHg at 25°C
• Boiling Point: 253.9°C at 760 mmHg
• Flash Point: 105.3°C
• PSA: 52.60000
• Density: 1.36g/cm³
• LogP: 0.54720
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 213.9799641
• Heavy Atom Count: 12
• Complexity: 162

Purity/Quality:

99% ^*data from raw suppliers

2 3-DICHLOROSUCCINIC ACID DIMETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(C(C(=O)OC)Cl)Cl

Technology Process of Dimethyl 2,3-dichlorosuccinate

There total 11 articles about Dimethyl 2,3-dichlorosuccinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oct-1-ene (111-66-0,25068-25-1) + Bromo-chloro-phenyl-acetic acid methyl ester → dimethyl α,α'-dichloro-succinates (62173-55-1)

Guidance literature:

With iron; copper(I) bromide; In dichloromethane; N,N-dimethyl-formamide; for 48h; Yield given; Ambient temperature;

DOI:10.1016/0040-4039(95)00256-C

Reference yield:

dimethyl L-tartrate (608-68-4) → dimethyl α,α'-dichloro-succinates (62173-55-1)

Guidance literature:

With pyridine; thionyl chloride; at 70 ℃; levorotatory α.α'-dichlorosuccinic acid dimethyl ester;

Reference yield:

dimethyl D/L-tartrate (608-69-5) → dimethyl α,α'-dichloro-succinates (62173-55-1)

Guidance literature:

With pyridine; thionyl chloride; at 70 ℃;

upstream raw materials:

methanol

racem.-2,3-dichloro-succinic acid

d,l-dichlorosuccinic acid

dimethyl L-tartrate

Downstream raw materials:

Dimethyl succinate

dimethyl chloromaleate

Refernces

• 1、 Syvret, Robert G.,Vassilaros, Daniel L.,Parees, David M.,Pez, Guido P.. "The formation of halogenated succinates by liquid-phase direct fluorination with elemental fluorine". . p. 277 - 282. Retrieved 2007/10/02.