(E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Base Information

Chemical Name:(E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate
CAS No.:1585241-40-2
Molecular Formula:C₂HF₃O₂*C₁₇H₁₉ClN₂
Molecular Weight:400.828
Hs Code.:

Synonyms:(E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Suppliers and Price of (E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

There total 3 articles about (E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 1694-57-1
(2-chlorophenyl)(pyridin-2-yl)methanone

: 18355-96-9
(3-dimethylaminopropyl)-triphenylphosphoniumbromide

: 76-05-1
trifluoroacetic acid

: 1585241-40-2
(E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Guidance literature:: (3-dimethylaminopropyl)-triphenylphosphoniumbromide; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 0.25h;

(2-chlorophenyl)(pyridin-2-yl)methanone; In tetrahydrofuran; at 20 ℃; for 24h;

trifluoroacetic acid; In water;
DOI:10.1021/ml5000228

Reference yield:

: 109-04-6
2-bromo-pyridine

: 1585241-40-2
(E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / cyclohexane; tetrahydrofuran; diethyl ether / 0.25 h / -85 - -10 °C

1.2: 24 h / -110 - 20 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / 0 °C

2.2: 24 h / 20 °C

With n-butyllithium; lithium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; cyclohexane; 2.1: |Wittig Olefination / 2.2: |Wittig Olefination;
DOI:10.1021/ml5000228

Reference yield:

: 610-96-8
methyl chlorobenzoate

: 1585241-40-2
(E)-4-(2-chlorophenyl)-N,N-dimethyl-4-(2-pyridyl)but-3-en-1-ammonium trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / cyclohexane; tetrahydrofuran; diethyl ether / 0.25 h / -85 - -10 °C

1.2: 24 h / -110 - 20 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / 0 °C

2.2: 24 h / 20 °C

With n-butyllithium; lithium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; cyclohexane; 2.1: |Wittig Olefination / 2.2: |Wittig Olefination;
DOI:10.1021/ml5000228