Technology Process of C25H25NO2
There total 6 articles about C25H25NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C24H23NO2;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 ℃;
for 1h;
Inert atmosphere;
methyl iodide;
In
N,N-dimethyl-formamide; mineral oil;
at 0 - 20 ℃;
for 19h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2012.10.092
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetone / 5 h / Reflux; Inert atmosphere
2.1: potassium carbonate; copper / Triethylene glycol dimethyl ether / 48 h / 140 °C / Inert atmosphere
2.2: 15 h / 20 - 140 °C / Inert atmosphere
3.1: tetrahydrofuran; diethyl ether / -78 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C / Inert atmosphere
4.2: 19 h / 0 - 20 °C / Inert atmosphere
With
copper; sodium hydride; potassium carbonate;
In
tetrahydrofuran; diethyl ether; Triethylene glycol dimethyl ether; N,N-dimethyl-formamide; acetone; mineral oil;
DOI:10.1016/j.tetlet.2012.10.092
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate; copper / Triethylene glycol dimethyl ether / 48 h / 140 °C / Inert atmosphere
1.2: 15 h / 20 - 140 °C / Inert atmosphere
2.1: tetrahydrofuran; diethyl ether / -78 °C / Inert atmosphere
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C / Inert atmosphere
3.2: 19 h / 0 - 20 °C / Inert atmosphere
With
copper; sodium hydride; potassium carbonate;
In
tetrahydrofuran; diethyl ether; Triethylene glycol dimethyl ether; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.tetlet.2012.10.092
