Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide

Base Information

Chemical Name:Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide
CAS No.:137927-78-7
Molecular Formula:C₁₅H₁₅FN₄O₂S
Molecular Weight:334.374
Hs Code.:
DSSTox Substance ID:DTXSID30160404
Nikkaji Number:J442.247C
Mol file:137927-78-7.mol

Synonyms:137927-78-7;BRN 5451734;Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide;2-[6-(4-fluorophenoxy)pyrimidin-4-yl]sulfanyl-N-(propan-2-ylideneamino)acetamide;((6-(4-Fluorophenoxy)-4-pyrimidinyl)thio)acetic acid (1-methylethylidene)hydrazide;C15H15FN4O2S;DTXSID30160404;IJDPVAIJEKZOCY-UHFFFAOYSA-N;C15-H15-F-N4-O2-S;((6-(4-Fluorophenoxy)-4-pyrimidinyl)thio)acetic acid(1-methylethylidene)hydrazide

Suppliers and Price of Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:12.33±0.46(Predicted)
Flash Point:°C
PSA：105.26000
Density:1.3g/cm³
LogP:3.85240
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:334.08997507
Heavy Atom Count:23
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=NNC(=O)CSC1=NC=NC(=C1)OC2=CC=C(C=C2)F)C

Technology Process of Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide

There total 2 articles about Acetic acid, ((6-(4-fluorophenoxy)-4-pyrimidinyl)thio)-, (1-methylethylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 137927-74-3
[6-(4-Fluoro-phenoxy)-pyrimidin-4-ylsulfanyl]-acetic acid hydrazide

: 67-64-1
acetone

: 137927-78-7
[6-(4-Fluoro-phenoxy)-pyrimidin-4-ylsulfanyl]-acetic acid isopropylidene-hydrazide

Guidance literature:: for 0.5h; Ambient temperature;
DOI:10.1007/BF00767268

Reference yield:

: 124041-07-2
ethyl <6-(4-fluorophenoxy)-4-pyrimidinylthio>acetate

: 137927-78-7
[6-(4-Fluoro-phenoxy)-pyrimidin-4-ylsulfanyl]-acetic acid isopropylidene-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / hydrazine hydrate / ethanol / 0.5 h / Ambient temperature

2: 85 percent / 0.5 h / Ambient temperature

With hydrazine hydrate; In ethanol;
DOI:10.1007/BF00767268