1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Base Information

Chemical Name:1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan
CAS No.:207731-95-1
Molecular Formula:C₂₆H₂₉NO₆S
Molecular Weight:483.585
Hs Code.:

Synonyms:1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Suppliers and Price of 1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

There total 35 articles about 1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 186351-18-8
1,2,3,3a(R),8,9,9a(R),9b(S)-octahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

: 207731-95-1
1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Guidance literature:: With N-Bromosuccinimide; triethylamine; dibenzoyl peroxide; In tetrachloromethane; for 0.666667h; Heating;
DOI:10.1021/jo9805394

Reference yield:

: 186351-22-4
1,2,3,3a(R),8,9,9a(S),9b(S)-octahydro-7-chloro-9b-ethenyl-5-methoxy-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

: 207731-95-1
1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Guidance literature:: Multi-step reaction with 4 steps

1.1: BH₃*SMe₂ / tetrahydrofuran / 21 h / -15 - 20 °C

1.2: 78 percent / NaOH; H₂O₂ / tetrahydrofuran; H₂O / 20 h / 20 °C

2.1: 98 percent / H₂; potassium hydroxide / Raney nickel / methanol / 5 h / 20 °C

3.1: 88 percent / tributylphosphane; 1,1'-(azodicarbonyl)dipiperidine / benzene / 24.2 h / 0 - 20 °C

4.1: 85 percent / NBS; benzoyl peroxide; Et₃N / CCl₄ / 0.67 h / Heating

With potassium hydroxide; N-Bromosuccinimide; tributylphosphine; dimethylsulfide borane complex; hydrogen; triethylamine; 1,1'-azodicarbonyl-dipiperidine; dibenzoyl peroxide; nickel; In tetrahydrofuran; methanol; tetrachloromethane; benzene; 1.1: Addition / 1.2: Oxidation / 2.1: Hydrogenolysis / 3.1: Mitsunobu reaction / 4.1: Dehydrogenation;
DOI:10.1021/jo9805394

Reference yield:

: 213619-55-7
1,2,3,3a(R),8,9,9a(R),9b(S)-octahydro-7-chloro-5-methoxy-9b-(2-hydroxyethyl)-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

: 207731-95-1
1,2,3,3a(R),9a(R),9b(S)-hexahydro-5-methoxy-9b-[2-[N-methyl-N-(phenylsulfonyl)amino]ethyl]-3-(ethylenedioxy)phenanthro[4,4a,4b,5-bcd]furan

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂; potassium hydroxide / Raney nickel / methanol / 5 h / 20 °C

2: 88 percent / tributylphosphane; 1,1'-(azodicarbonyl)dipiperidine / benzene / 24.2 h / 0 - 20 °C

3: 85 percent / NBS; benzoyl peroxide; Et₃N / CCl₄ / 0.67 h / Heating

With potassium hydroxide; N-Bromosuccinimide; tributylphosphine; hydrogen; triethylamine; 1,1'-azodicarbonyl-dipiperidine; dibenzoyl peroxide; nickel; In methanol; tetrachloromethane; benzene; 1: Hydrogenolysis / 2: Mitsunobu reaction / 3: Dehydrogenation;
DOI:10.1021/jo9805394