2-Amino-2-cyclopentylacetic acid

Base Information

• Chemical Name: 2-Amino-2-cyclopentylacetic acid
• CAS No.: 933-95-9
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.186
• Hs Code.: 2922499990
• European Community (EC) Number: 841-125-8
• NSC Number: 12751
• UNII: UU47F8DM2N
• DSSTox Substance ID: DTXSID70918522
• Mol file: 933-95-9.mol

Synonyms:2-amino-2-cyclopentylacetic acid;933-95-9;Cyclopentaneglycine;D-Cyclopentylglycine;Cyclopentaneacetic acid, alpha-amino-;2-cyclopentylglycine;alpha-Aminocyclopentaneacetic acid;Amino-cyclopentyl-acetic acid;DL-cyclopentylglycine;MFCD09264351;NSC-12751;amino(cyclopentyl)acetic acid;DL-2-Cyclopentylglycine;MFCD03788075;MFCD03788076;NSC12751;2521-82-6;2-cyclopentyl-DL-glycine;UU47F8DM2N;SCHEMBL623280;2-amino-2-cyclopentylaceticacid;alpha-aminocyclopentylacetic acid;BERBERINECHLORIDEDIHYDRATE;DTXSID70918522;alpha-Amino-cyclopentaneacetic acid;AMY22039;AKOS000189969;AKOS016344416;AB15907;AB15910;CS-W021543;HY-W040803;SB40032;DS-18429;SY007465;SY110328;SY111496;BB 0261558;FT-0600054;FT-0651901;FT-0693031;A21852;EN300-145270;2-Amino-2-cyclopentylacetic acid (H-DL-Gly(cPent)-OH);F2124-1141

Chemical Property of 2-Amino-2-cyclopentylacetic acid

Chemical Property:

• Boiling Point: 277oC
• PKA: 2.49±0.10(Predicted)
• Flash Point: 121oC
• PSA: 63.32000
• Density: 1.167
• LogP: 1.28880
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 143.094628657
• Heavy Atom Count: 10
• Complexity: 130

Purity/Quality:

99%+, ^*data from raw suppliers

2-amino-2-cyclopentylaceticacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)C(C(=O)O)N

Technology Process of 2-Amino-2-cyclopentylacetic acid

There total 8 articles about 2-Amino-2-cyclopentylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetamido-2-cyclopentylacetic acid (2521-83-7) → cyclopentylglycine (933-95-9,2521-82-6)

Guidance literature:

With hydrogenchloride;

Reference yield:

4-cyclopentylidene-2-phenyloxazol-5(4H)-one (59759-76-1) → cyclopentylglycine (933-95-9,2521-82-6)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, aq. NH₃ / Pd-C / ethanol

2: aq. HCl / Heating

With hydrogenchloride; ammonium hydroxide; hydrogen; palladium on activated charcoal; In ethanol;

Reference yield:

→ cyclopentylglycine (933-95-9,2521-82-6)

Guidance literature:

With ammonium hydroxide;

upstream raw materials:

2-thioxo-4-cyclopentylidene-5-thiazolidinone

N-Benzoyl-α-cyclopentylglycine amide

Cyclopentyl bromide

cyclopentanone

Downstream raw materials:

(S)-2-amino-2-cyclopentylacetic acid

Refernces