[3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether

Base Information

Chemical Name:[3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether
CAS No.:952711-05-6
Molecular Formula:C₂₈H₂₈F₃NO₃
Molecular Weight:483.53
Hs Code.:

Synonyms:[3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether

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Chemical Property of [3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether

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Technology Process of [3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether

There total 1 articles about [3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 952709-82-9
(2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-acetic acid ethyl ester

: 343604-24-0
2-(4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetaldehyde

: 952711-05-6
[3-(4'-trifluoromethyl-biphenyl-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy]-acetic acid ethyl ether

Guidance literature:: (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-acetic acid ethyl ester; 2-(4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetaldehyde; With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; Heating / reflux;

With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃;