propyl (4-chlorophenyl)carbamate

Base Information

• Chemical Name: propyl (4-chlorophenyl)carbamate
• CAS No.: 121449-90-9
• Molecular Formula: C₁₀H₁₂ClNO₂
• Molecular Weight: 213.664
• Hs Code.: 2924299090
• Mol file: 121449-90-9.mol

Synonyms:PropylN-(4-chlorophenyl)carbamate

Chemical Property of propyl (4-chlorophenyl)carbamate

Chemical Property:

• Vapor Pressure: 0.0136mmHg at 25°C
• Boiling Point: 258.6°C at 760 mmHg
• Flash Point: 110.2°C
• PSA: 38.33000
• Density: 1.229g/cm³
• LogP: 3.37150

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of propyl (4-chlorophenyl)carbamate

There total 6 articles about propyl (4-chlorophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-Chloro-4-iodobenzene (637-87-6) + 1-propyl carbamate (627-12-3) → 1-propyl (4-chlorophenyl)carbamate (121449-90-9)

Guidance literature:

With C₃₂H₅₂N₂O₈PdSi₂; sodium t-butanolate; In toluene; at 100 ℃; chemoselective reaction;

DOI:10.1039/c6ra17268g

Reference yield: 92.0%

carbon dioxide (124-38-9,18923-20-1) + 4-chloro-aniline (106-47-8) + propyl bromide (106-94-5) → 1-propyl (4-chlorophenyl)carbamate (121449-90-9)

Guidance literature:

With choline chloride * 2ZnCl₂; at 20 ℃; for 2h; under 760.051 Torr; Green chemistry;

DOI:10.1039/c9nj02810b

Reference yield: 88.0%

bromochlorobenzene (106-39-8) + 1-propyl carbamate (627-12-3) → 1-propyl (4-chlorophenyl)carbamate (121449-90-9)

Guidance literature:

With C₃₂H₅₂N₂O₈PdSi₂; sodium t-butanolate; In toluene; at 100 ℃; chemoselective reaction;

DOI:10.1039/c6ra17268g

upstream raw materials:

1-Chloro-4-iodobenzene

1-propyl carbamate

bromochlorobenzene

propan-1-ol

Refernces

• 1、 Sardarian, Ali Reza,Dindarloo Inaloo, Iman,Zangiabadi, Milad. "An Fe3O4@SiO2/Schiff base/Cu(ii) complex as an efficient recyclable magnetic nanocatalyst for selective mono: N-arylation of primary O-alkyl thiocarbamates and primary O-alkyl carbamates with aryl halides and arylboronic acids". . p. 8557 - 8565. Retrieved 2019/06/14.
• 2、 Sardarian, Ali Reza,DindarlooInaloo, Iman,Zangiabadi, Milad. "Selective Synthesis of Secondary Arylcarbamates via Efficient and Cost Effective Copper-Catalyzed Mono Arylation of Primary Carbamates with Aryl Halides and Arylboronic Acids". . p. 642 - 652. Retrieved 2018/01/11.