4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

Base Information

Chemical Name:4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate
CAS No.:1146090-01-8
Molecular Formula:C₂HF₃O₂*C₁₇H₁₈N₂O₃
Molecular Weight:412.365
Hs Code.:

Synonyms:4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

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Chemical Property of 4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

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Technology Process of 4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

There total 1 articles about 4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1146089-99-7
3-[6-(4-methoxycarbonyl-3-methylphenyl)pyridin-3-yloxy]azetidine-1-carboxylic acid tert-butyl ester

: 76-05-1
trifluoroacetic acid

: 1146090-01-8
4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 1146090-01-8
4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

: 54042-97-6
5-chloromethyl-3-isopropyl-[1,2,4]oxadiazole

: 1146090-03-0
4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]pyridin-2-yl}-2-methylbenzoic acid methyl ester

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 40 ℃; for 16h;

Reference yield:

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 1146090-01-8
4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate

: 1146157-99-4
2-methyl-4-{5-[1-(4-trifluoromethylbenzyl)azetidin-3-yloxy]pyridine-2-yl}benzoic acid methyl ester

Guidance literature:: 4-[5-(azetidin-3-yloxy)pyridin-2-yl]-2-methylbenzoic acid methyl ester trifluoroacetate; With triethylamine; In dichloromethane; for 0.0833333h;

4-Trifluoromethylbenzaldehyde; With sodium tris(acetoxy)borohydride; In dichloromethane; for 17h;

With water; In dichloromethane;