(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Base Information

Chemical Name:(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt
CAS No.:1420837-35-9
Molecular Formula:C₂₉H₃₅F₆O₅*Na
Molecular Weight:600.574
Hs Code.:

(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Synonyms:(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Suppliers and Price of (S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

There total 6 articles about (S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: (S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxymethyl)dihydrofuran-2-one

: 1420837-35-9
(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Guidance literature:: With potassium hydroxide; In methanol; at 20 ℃; for 2h;
DOI:10.1016/j.bmc.2012.11.029

Reference yield:

: 865235-97-8
4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butynyl)phenyl]propyl}-2-methylphenol

: 1420837-35-9
(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h

1.2: 1 h

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

2.2: 15 h / 100 °C

3.1: hydrogenchloride / 1,4-dioxane; water / 20 °C

4.1: palladium hydroxide, 20 wt% on carbon; hydrogen / ethyl acetate / 20 °C

5.1: potassium hydroxide / methanol / 2 h / 20 °C

With hydrogenchloride; palladium hydroxide, 20 wt% on carbon; hydrogen; potassium carbonate; potassium hydroxide; In 1,4-dioxane; methanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2012.11.029

Reference yield:

: (S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-methoxymethoxy-3-trifluoromethyl-1-butynyl)phenyl]propyl}-2-methylphenoxymethyl)dihydrofuran-2-one

: 1420837-35-9
(S)-5-(4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethylbutyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / 1,4-dioxane; water / 20 °C

2: palladium hydroxide, 20 wt% on carbon; hydrogen / ethyl acetate / 20 °C

3: potassium hydroxide / methanol / 2 h / 20 °C

With hydrogenchloride; palladium hydroxide, 20 wt% on carbon; hydrogen; potassium hydroxide; In 1,4-dioxane; methanol; water; ethyl acetate;
DOI:10.1016/j.bmc.2012.11.029