tert-butyl 3,4-dichlorobenzylidenecarbamate

Base Information

• Chemical Name: tert-butyl 3,4-dichlorobenzylidenecarbamate
• CAS No.: 163226-27-5
• Molecular Formula: C₁₂H₁₃Cl₂NO₂
• Molecular Weight: 274.147
• Mol file: 163226-27-5.mol

Synonyms:tert-butyl 3,4-dichlorobenzylidenecarbamate

Chemical Property of tert-butyl 3,4-dichlorobenzylidenecarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 3,4-dichlorobenzylidenecarbamate

There total 4 articles about tert-butyl 3,4-dichlorobenzylidenecarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-dimethylethyl N-[(4-cyanophenyl)methylen]carbamate (150884-51-8) → tert-butyl 3,4-dichlorobenzylidenecarbamate (163226-27-5)

Guidance literature:

Multi-step reaction with 3 steps

1: LiMCPBA / CH₂Cl₂ / 2 h / -78 °C

2: CD₂Cl₂ / -94 °C

3: toluene / 30 h / Heating

With LiMCPBA; In dichloromethane; dichloromethane-d2; toluene;

DOI:10.1002/chem.19970031019

Reference yield:

triphenyl(t-butoxycarbonylimino)phosphorane (68014-21-1) + 3,4-dichlorobenzaldehyde (6287-38-3) → tert-butyl 3,4-dichlorobenzylidenecarbamate (163226-27-5)

Guidance literature:

In toluene; for 72h; Heating;

DOI:10.1016/0040-4039(95)00025-8

Reference yield:

N-(tert-butyloxycarbonyl) azide (1070-19-5) → tert-butyl 3,4-dichlorobenzylidenecarbamate (163226-27-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / diethyl ether

2: toluene / 30 h / Heating

In diethyl ether; toluene;

DOI:10.1002/chem.19970031019

upstream raw materials:

triphenyl(t-butoxycarbonylimino)phosphorane

3,4-dichlorobenzaldehyde

N-(tert-butyloxycarbonyl) azide

1,1-dimethylethyl N-[(4-cyanophenyl)methylen]carbamate

Downstream raw materials:

N-tert-butoxycarbonyl-3-(3,4-dichlorophenyl)oxaziridine

3,4-dichlorobenzaldehyde

Refernces

• 1、 Vidal, Joelle,Damestoy, Stephanie,Collet, Andre. "Electrophilic Amination Reagents: A New Method For The Preparation Of 3-Aryl-N-BOC (or N-FMOC) Oxaziridines". . p. 1439 - 1442. Retrieved 2007/10/02.