N-(2,4-dimethylphenyl)isobutyrimidamide

Base Information

Chemical Name:N-(2,4-dimethylphenyl)isobutyrimidamide
CAS No.:111296-09-4
Molecular Formula:C₁₂H₁₈N₂
Molecular Weight:190.288
Hs Code.:

Synonyms:N-(2,4-dimethylphenyl)isobutyrimidamide

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Chemical Property of N-(2,4-dimethylphenyl)isobutyrimidamide

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Technology Process of N-(2,4-dimethylphenyl)isobutyrimidamide

There total 1 articles about N-(2,4-dimethylphenyl)isobutyrimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 583-70-0
1-bromo-2,4-dimethylbenzene

: 22007-68-7
2-methylpropanimidamide hydrochloride

: 111296-09-4
N-(2,4-dimethylphenyl)isobutyrimidamide

Guidance literature:: 1-bromo-2,4-dimethylbenzene; 2-methylpropanimidamide hydrochloride; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; t-BuBrettPhos; caesium carbonate; In tert-butyl alcohol; at 20 ℃; for 0.0166667h; Inert atmosphere; Sonication;

In tert-butyl alcohol; at 85 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ol301700y