Technology Process of C24H28FNO6
There total 4 articles about C24H28FNO6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisopropylamine;
In
1,4-dioxane; hexane;
at 60 ℃;
Inert atmosphere;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 2 steps
1: diisobutylaluminium hydride / dichloromethane / 2 h / -78 - 0 °C / Inert atmosphere
2: copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisopropylamine / 1,4-dioxane; hexane / 60 °C / Inert atmosphere
With
copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisobutylaluminium hydride; diisopropylamine;
In
1,4-dioxane; hexane; dichloromethane;
2: Sonogashira coupling;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 3 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere
2: diisobutylaluminium hydride / dichloromethane / 2 h / -78 - 0 °C / Inert atmosphere
3: copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisopropylamine / 1,4-dioxane; hexane / 60 °C / Inert atmosphere
With
copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; di-isopropyl azodicarboxylate; diisobutylaluminium hydride; diisopropylamine; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane;
3: Sonogashira coupling;
DOI:10.1021/jm2007062
