Carbamic acid, 2-propynyl-, 1-(3,5-dimethoxyphenyl)-1-methylethylester

Base Information

• Chemical Name: Carbamic acid, 2-propynyl-, 1-(3,5-dimethoxyphenyl)-1-methylethylester
• CAS No.: 811867-16-0
• Molecular Formula: C15H19NO4
• Molecular Weight: 277.32
• Mol file: 811867-16-0.mol

Synonyms:

Chemical Property of Carbamic acid, 2-propynyl-, 1-(3,5-dimethoxyphenyl)-1-methylethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid, 2-propynyl-, 1-(3,5-dimethoxyphenyl)-1-methylethylester

There total 1 articles about Carbamic acid, 2-propynyl-, 1-(3,5-dimethoxyphenyl)-1-methylethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.2%

(3’,5’-dimethoxy-1,1-dimethylbenzyloxy)carbonyl azide (39508-01-5) + Propargylamine (2450-71-7) → Ddz-propargylamine (811867-16-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; N,N,N',N'-tetramethylguanidine; In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere;

Reference yield: 100.0%

Ddz-propargylamine (811867-16-0) + (S)-1-(2-iodophenoxy)-2-propanol (1014984-81-6) → C24H29NO6 (1014984-83-8)

Guidance literature:

With triethylamine; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; In acetonitrile; at 20 ℃; Inert atmosphere;

Reference yield: 100.0%

Ddz-propargylamine (811867-16-0) + C9H11IO2 (811867-46-6) → C24H29NO6 (811867-47-7)

Guidance literature:

With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1021/jm2007062

upstream raw materials:

(3’,5’-dimethoxy-1,1-dimethylbenzyloxy)carbonyl azide

Propargylamine

Downstream raw materials:

[3-(2-hydroxymethyl-2H-chromen-8-yl)-prop-2-ynyl]-carbamic acid 3,5-dimethoxybenzyl ester

C₂₅H₂₈FNO₇

C₂₄H₂₉NO₆

C₂₄H₃₃NO₆

Refernces