Technology Process of 3,5-Dichlor-4-methoxy-(2-amino-2-methylpropyl)benzol
There total 6 articles about 3,5-Dichlor-4-methoxy-(2-amino-2-methylpropyl)benzol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
nickel;
In
methanol;
at 100 ℃;
for 3h;
under 114000 Torr;
Yield given;
DOI:10.1002/ardp.19833160303
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 21.3 percent / NaOH / H2O / 192 h / 70 °C
2: 26 percent / KF*2H2O, tetrabutylammonium chloride / 30 h / Heating
3: 86 percent / 1.) tetrabutylammonium hydroxide, 50percent aq. NaOH / CH2Cl2 / 1.) 10 min, 2.) 5 h
4: H2 / Raney-Ni / methanol / 3 h / 100 °C / 114000 Torr
With
sodium hydroxide; tetra(n-butyl)ammonium hydroxide; hydrogen;
potassium fluoride; tetrabutyl-ammonium chloride; nickel;
In
methanol; dichloromethane; water;
DOI:10.1002/ardp.19833160303
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 71 percent / KF*2H2O, tetrabutylammonium chloride / 30 h / Heating
2: 76 percent / tert-butyl hypochloride / CCl4 / 3 h / Heating
3: 86 percent / 1.) tetrabutylammonium hydroxide, 50percent aq. NaOH / CH2Cl2 / 1.) 10 min, 2.) 5 h
4: H2 / Raney-Ni / methanol / 3 h / 100 °C / 114000 Torr
With
sodium hydroxide; tert-butylhypochlorite; tetra(n-butyl)ammonium hydroxide; hydrogen;
potassium fluoride; tetrabutyl-ammonium chloride; nickel;
In
methanol; tetrachloromethane; dichloromethane;
DOI:10.1002/ardp.19833160303
