(3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate

Base Information

• Chemical Name: (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate
• CAS No.: 1615707-42-0
• Molecular Formula: C₂₇H₄₄B₂O₆
• Molecular Weight: 486.265

Synonyms:(3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate

Chemical Property of (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate

There total 4 articles about (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H42B2O5 (1615707-40-8) + acetic anhydride (108-24-7) → (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate (1615707-42-0)

Guidance literature:

With dmap; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja504228p

Reference yield:

(3S,4R)-3-methyl-6-phenyl-1-hexen-4-ol (83173-74-4,89103-73-1,104011-57-6,106756-95-0,129170-74-7,89103-74-2) → (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate (1615707-42-0)

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate / tetrahydrofuran; methanol / 6 h / 70 °C / Inert atmosphere

2: dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere

With dmap; caesium carbonate; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1021/ja504228p

Reference yield:

bis(pinacol)diborane (73183-34-3) → (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate (1615707-42-0)

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate / tetrahydrofuran; methanol / 6 h / 70 °C / Inert atmosphere

2: dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere

With dmap; caesium carbonate; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1021/ja504228p

upstream raw materials:

C₂₅H₄₂B₂O₅

acetic anhydride

bis(pinacol)diborane

(3S,4R)-3-methyl-6-phenyl-1-hexen-4-ol

Downstream raw materials:

tert-butyldiphenyl(((4R,5R,6R)-2,2,5-trimethyl-6-phenethyl-1,3-dioxan-4-yl)methoxy)silane

C₃₁H₄₀O₄Si

C₁₅H₂₂O₄

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1615707-42-0 (3R,4S,5S)-4-methyl-1-phenyl-5,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexan-3-yl acetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send