5-[7-Methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole

Base Information

Chemical Name:5-[7-Methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole
CAS No.:23357-64-4
Molecular Formula:C₂₀H₁₈O₄
Molecular Weight:322.361
Hs Code.:
Mol file:23357-64-4.mol

Synonyms:1,3-Benzodioxole,5-[7-methoxy-3-methyl-5-(1-propenyl)-2-benzofuranyl]-, (E)-; 1,3-Benzodioxole,5-[7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl]- (9CI); Benzofuran,7-methoxy-3-methyl-2-[3,4-(methylenedioxy)phenyl]-5-propenyl-, (E)- (8CI);Eupomatene; Eupomatenoid 1

Suppliers and Price of 5-[7-Methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-[7-Methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole

Chemical Property:

PSA：40.83000
LogP:5.17860

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-[7-Methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole

There total 23 articles about 5-[7-Methoxy-3-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 133658-66-9
C₂₄H₃₁N₂O₆P

: 23357-64-4
eupomatenoid-1

Guidance literature:: With formic acid; for 0.5h; Heating;
DOI:10.1248/cpb.39.41

Reference yield:

: 105494-65-3,66680-85-1,66680-84-0
(E)-propenyl-tri-n-butylstannane

: 183370-08-3
5-(5-Iodo-7-methoxy-3-methyl-benzofuran-2-yl)-benzo[1,3]dioxole

: 23357-64-4
eupomatenoid-1

Guidance literature:: With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; trifuran-2-yl-phosphane; lithium chloride; In N,N-dimethyl-formamide; at 120 - 130 ℃; Yield given;
DOI:10.1016/0040-4039(96)01619-X

Reference yield:

: 97-53-0
4-allylguaiacol

: 23357-64-4
eupomatenoid-1

Guidance literature:: Multi-step reaction with 6 steps

1: hydrogen / palladium-carbon / ethyl acetate

2: boron trifluoride / 1.5 h / 150 - 155 °C

3: mossy zinc, mercury(II) chloride, 50percent hydrochloric acid / ethanol / 12 h / Heating

4: 1.83 g / pyridine / 42 h / Ambient temperature

5: 67 percent / N-bromosuccinimide / CCl₄ / 0.5 h / Heating

6: 1.) triphenylphosphine, 2.) triethylamine / 1.) acetonitrile, reflux, 35 h, 2.) toluene, reflux

With pyridine; hydrogenchloride; N-Bromosuccinimide; boron trifluoride; hydrogen; triethylamine; triphenylphosphine; mercury dichloride; zinc; palladium on activated charcoal; In tetrachloromethane; ethanol; ethyl acetate;