(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane

Base Information

• Chemical Name: (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane
• CAS No.: 131755-77-6
• Molecular Formula: C₄₃H₆₂O₇Si
• Molecular Weight: 719.047
• Mol file: 131755-77-6.mol

Synonyms:(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane

Chemical Property of (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane

There total 7 articles about (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

mesitaldehyde dimethylacetal (64761-29-1) + (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol (131755-76-5) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane (131755-77-6)

Guidance literature:

With camphor-10-sulfonic acid; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(01)85585-X

Reference yield: 76.0%

t-butyldimethylsiyl triflate (69739-34-0) + Benzoic acid (R)-2-[(2R,4S,5S,6R)-6-[(1R,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-1-methyl-butyl]-5-methyl-2-(2,4,6-trimethyl-phenyl)-[1,3]dioxan-4-yl]-propyl ester → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane (131755-77-6)

Guidance literature:

DOI:10.1016/S0040-4020(01)85585-X

Reference yield:

Benzoic acid (2R,3S,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester (114811-23-3) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane (131755-77-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent

2: 76 percent

DOI:10.1016/S0040-4020(01)85585-X

upstream raw materials:

mesitaldehyde dimethylacetal

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol

t-butyldimethylsiyl triflate

Benzoic acid (2R,3S,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester

Downstream raw materials:

C₇₅H₁₀₆O₁₂SSi₂

(1EZ,3R,4S,5S,6R,7R,8R)-1-Benzoyloxy-7-<(1,1-dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)dec-1-ene

(3R,4S,5S,6R,7R,8R)-7-<(1,1-Dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)decan-1-ol

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal