N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine

Base Information

• Chemical Name: N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine
• CAS No.: 1190115-53-7
• Molecular Formula: C₁₅H₁₇N₅O₄S₂
• Molecular Weight: 395.463

Synonyms:N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine

Chemical Property of N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine

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Technology Process of N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine

There total 1 articles about N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-(isopropylsulfonyl)phenyl)-2-(methylthio)pyrazolo[1,5-a][1,3,5]triazine (1190115-52-6) → N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine (1190115-53-7)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In 1,2-dichloro-ethane; at 0 - 20 ℃;

Reference yield:

2-isopropoxy-5-methyl-4-(1-methyl-piperidin-4-yl)-phenylamine (1032903-66-4) + N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine (1190115-53-7) → N2-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrazolo[1,5-a][1,3,5]triazine-2,4-diamine (1190115-51-5)

Guidance literature:

With toluene-4-sulfonic acid; In isopropyl alcohol; at 150 ℃; for 3h;

Reference yield:

N-(2-(isopropylsulfonyl)phenyl)-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazine (1190115-53-7) + 2-methoxy-5-methyl-4-(piperidin-4-yl)aniline trifluoroacetate → N4-(2-(isopropylsulfonyl)phenyl)-N-(2-methoxy-5-methyl-4-(piperidin-4-yl)phenyl)pyrazolo[1,5-a][1,3,5]triazine-2,4-diamine trifluoroacetate

Guidance literature:

With trifluoroacetic acid; In isopropyl alcohol; at 150 ℃; for 3h;

upstream raw materials:

N-(2-(isopropylsulfonyl)phenyl)-2-(methylthio)pyrazolo[1,5-a][1,3,5]triazine

Downstream raw materials:

N₂-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)pyrazolo[1,5-a][1,3,5]triazine-2,4-diamine

(R)-(4-(4-(4-(2-(isopropylsulfonyl)phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)-5-methoxy-2-methylphenyl)piperidin-1-yl)(morpholin-3-yl)methanone

(R)-tert-butyl 3-(4-(4-(4-(2-(isopropylsulfonyl)phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)-5-methoxy-2-methylphenyl)piperidine-1-carbonyl)morpholine-4-carboxylate

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