(3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

Base Information

Chemical Name:(3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one
CAS No.:1273328-77-0
Molecular Formula:C₂₀H₂₃NO₄
Molecular Weight:341.407
Hs Code.:

Synonyms:(3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

Suppliers and Price of (3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

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Chemical Property of (3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

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Technology Process of (3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

There total 3 articles about (3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1220353-57-0
(2R)-4-(3,4-dimethoxyphenyl)-4-oxo-2-{[(1R)-1-phenylethyl]amino}butanoic acid

: 1273328-77-0
(3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 20 °C

2: hydrogenchloride / water / 40 °C

3: potassium carbonate / water

With hydrogenchloride; sodium tetrahydroborate; potassium carbonate; In methanol; water;
DOI:10.1021/ol2001057

Reference yield:

: 1273328-68-9
C₂₀H₂₅NO₅

: 1273328-77-0
(3R,5R)-5-(3'',4''-dimethoxyphenyl)-3-((R)-1-phenylethylamino)-dihydrofuran-2(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / water / 40 °C

2: potassium carbonate / water

With hydrogenchloride; potassium carbonate; In water;
DOI:10.1021/ol2001057