1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate
CAS No.:1123306-70-6
Molecular Formula:C₁₇H₂₃F₃N₂O₄S
Molecular Weight:408.442
Hs Code.:

Synonyms:1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate

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Chemical Property of 1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate

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Technology Process of 1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate

There total 1 articles about 1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 708274-46-8,348165-63-9
1,1-dimethylethyl (2S,4R)-4-amino-2-methyl-1-pyrrolidinecarboxylate

: 777-44-6
3-(Trifluoromethyl)benzenesulfonyl chloride

: 1123306-70-6
1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 3h;

Reference yield:

: 506-68-3
bromocyane

: 1123306-70-6
1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate

: 1123308-03-1
N-[(3R,5S)-1-cyano-5-methyl-3-pyrrolidinyl]-3-(trifluoromethyl)benzenesulfonamide

Guidance literature:: 1,1-dimethylethyl (2S,4R)-2-methyl-4-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)-1-pyrrolidinecarboxylate; With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 3h;

With N-ethyl-N,N-diisopropylamine; In dichloromethane;

bromocyane; more than 3 stages;