1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid

Base Information

Chemical Name:1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid
CAS No.:86400-53-5
Molecular Formula:C₁₇H₁₅NO₃
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID101158841

Synonyms:DTXSID101158841;1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid;86400-53-5

Suppliers and Price of 1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:403

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C(=O)NC2=C1C=C(C=C2)C(=O)O)CC3=CC=CC=C3

Technology Process of 1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid

There total 4 articles about 1,2,3,4-Tetrahydro-2-oxo-3-(phenylmethyl)-6-quinolinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 86413-23-2
3,6-dicarbethoxy-3-benzyl-3,4-dihydro-quinolin-2(1H)-one

: 86400-53-5
3-benzyl-3,4-dihydro-quinolin-2(1H)-one-6-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 15h; Heating;

Reference yield:

: 30650-90-9
3-methyl-4-nitro-benzoic acid ethyl ester

: 86400-53-5
3-benzyl-3,4-dihydro-quinolin-2(1H)-one-6-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 60 percent / N-bromosuccinimide/benzoyl peroxide / CCl₄ / 5 h / Heating

2: 65 percent / sodium ethylate / ethanol

3: 50 percent / Fe powder / acetic acid / 1 h / Heating

4: 90 percent / 4N KOH / aq. ethanol / 15 h / Heating

With potassium hydroxide; N-Bromosuccinimide; sodium ethanolate; iron; dibenzoyl peroxide; In tetrachloromethane; ethanol; acetic acid;

Reference yield:

: 86400-51-3
3-bromomethyl-4-nitro-benzoic acid ethyl ester

: 86400-53-5
3-benzyl-3,4-dihydro-quinolin-2(1H)-one-6-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / sodium ethylate / ethanol

2: 50 percent / Fe powder / acetic acid / 1 h / Heating

3: 90 percent / 4N KOH / aq. ethanol / 15 h / Heating

With potassium hydroxide; sodium ethanolate; iron; In ethanol; acetic acid;