(R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol

Base Information

Chemical Name:(R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol
CAS No.:135711-19-2
Molecular Formula:C₁₂H₁₇NO
Molecular Weight:191.273
Hs Code.:
DSSTox Substance ID:DTXSID101295588
Nikkaji Number:J2.165.951G

Synonyms:SCHEMBL3583059;YQDISZZVFYLYOG-LBPRGKRZSA-N;DTXSID101295588;(R)-beta-Pyrrolizinophenethyl alcohol;(betaR)-beta-Phenyl-1-pyrrolidineethanol;(R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol;2-(R)-phenyl-2-(pyrrolidin-1-yl)ethanol;135711-19-2

Suppliers and Price of (R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:191.131014166
Heavy Atom Count:14
Complexity:160

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(C1)C(CO)C2=CC=CC=C2
Isomeric SMILES:C1CCN(C1)[C@@H](CO)C2=CC=CC=C2

Technology Process of (R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol

There total 2 articles about (R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 110-52-1
1,4-dibromo-butane

: 56613-80-0
D-2-phenylglycinol

: 135711-19-2
(2R)-2-phenyl-2-pyrrolidin-1-yl-ethanol

Guidance literature:: With sodium carbonate; In isopropyl alcohol; for 14h; Heating;
DOI:10.1016/j.tetlet.2005.03.101

Reference yield:

: 123-75-1
pyrrolidine

: 20780-54-5
(S)-styrene oxide

: 128821-02-3
(S)-2-(pyrrolidin-1-yl)-1-phenylethanol

: 135711-19-2
(2R)-2-phenyl-2-pyrrolidin-1-yl-ethanol

Guidance literature:: With graphene oxide; In neat (no solvent); at 20 ℃; for 16h; Overall yield = 91 %; enantioselective reaction; Green chemistry;
DOI:10.1002/cctc.201600241