3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

Base Information

Chemical Name:3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride
CAS No.:724794-66-5
Molecular Formula:C₁₈H₂₁N₂O*Cl
Molecular Weight:316.831
Hs Code.:

Synonyms:3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

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Technology Process of 3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

There total 4 articles about 3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1181444-59-6
N-(2-iodoethyl)-2,4,6-trimethylbenzenaminium chloride

: 122-51-0
orthoformic acid triethyl ester

: 95-55-6
2-amino-phenol

: 724794-66-5
3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

Guidance literature:: With formic acid; at 120 ℃;
DOI:10.1021/ol901189m

Reference yield:

: 724794-61-0
N-2-hydroxyphenyl-N'-mesityloxalamide

: 122-51-0
orthoformic acid triethyl ester

: 724794-66-5
3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

Guidance literature:: With hydrogenchloride; BH₃-THF; In tetrahydrofuran; methanol;

Reference yield:

: 79354-30-6
2-(2,4,6-trimethylphenylamino)-2-oxoacetic acid ethyl ester

: 724794-66-5
3-(2-hydroxyphenyl)-1-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / toluene / Reflux

2: borane-THF

With borane-THF; triethylamine; In toluene;
DOI:10.1016/j.jorganchem.2018.02.018