(3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

Base Information

Chemical Name:(3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CAS No.:41552-82-3
Molecular Formula:C15H21N5O4
Molecular Weight:335.36
Hs Code.:29349990
DSSTox Substance ID:DTXSID80961807
Mol file:41552-82-3.mol

Synonyms:SCHEMBL12200134;DTXSID80961807;PD057690

Suppliers and Price of (3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N6-Cyclopentyladenosine
50mg
$ 366.00

TRC
N6-Cyclopentyladenosine
100mg
$ 150.00

Tocris
N6-Cyclopentyladenosine ≥99%(HPLC)
50
$ 129.00

Sigma-Aldrich
N6-Cyclopentyladenosine solid
100mg
$ 209.00

Sigma-Aldrich
N6-Cyclopentyladenosine solid
25mg
$ 68.80

CSNpharm
N6-Cyclopentyladenosine
25mg
$ 52.00

CSNpharm
N6-Cyclopentyladenosine
100mg
$ 136.00

CSNpharm
N6-Cyclopentyladenosine
1g
$ 680.00

CSNpharm
N6-Cyclopentyladenosine
250mg
$ 245.00

Crysdot
(2R,3R,4S,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95+%
250mg
$ 242.00

Total 18 raw suppliers

Chemical Property of (3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

Chemical Property:

Vapor Pressure:4.71E-19mmHg at 25°C
Refractive Index:1.816
Boiling Point:673.4 °C at 760 mmHg
PKA:13.12±0.70(Predicted)
Flash Point:361.1 °C
PSA：125.55000
Density:1.78 g/cm³
LogP:-0.13470
Storage Temp.:2-8°C
Solubility.:H2O: soluble1.7mg/mL
XLogP3:0.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:335.15935417
Heavy Atom Count:24
Complexity:438

Purity/Quality:

97% ^*data from raw suppliers

N6-Cyclopentyladenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O
Isomeric SMILES:C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)C4[C@@H]([C@@H]([C@H](O4)CO)O)O
Uses N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist with Ki values of 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively and EC50 value of 18600 nM for hA2B. It has also shown its efficacy against organophosphate toxcity. N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.

Technology Process of (3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

There total 10 articles about (3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%