2-Phenyl-1,3-oxazole-4,5-dicarboxylic acid

Base Information

Chemical Name:2-Phenyl-1,3-oxazole-4,5-dicarboxylic acid
CAS No.:15926-44-0
Molecular Formula:C₁₁H₇NO₅
Molecular Weight:233.18
Hs Code.:
European Community (EC) Number:823-794-8
Nikkaji Number:J1.609.805A
ChEMBL ID:CHEMBL84112

Synonyms:2-phenyl-1,3-oxazole-4,5-dicarboxylic acid;15926-44-0;2-Phenyl-oxazole-4,5-dicarboxylic acid;CHEMBL84112;BDBM50102487;2-Phenyloxazole-4,5-dicarboxylic acid;2-phenyl-1,3-oxazole-4,5-dicarboxylicacid;EN300-1703736;Z1814519092

Suppliers and Price of 2-Phenyl-1,3-oxazole-4,5-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Phenyl-1,3-oxazole-4,5-dicarboxylic acid

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:233.03242232
Heavy Atom Count:17
Complexity:313

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=C(O2)C(=O)O)C(=O)O

Technology Process of 2-Phenyl-1,3-oxazole-4,5-dicarboxylic acid

There total 8 articles about 2-Phenyl-1,3-oxazole-4,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 144946-64-5
2-phenyl-oxazole-4,5-dicarboxylic acid dimethyl ester

: 15926-44-0
2-phenyl-oxazole-4,5-dicarboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1021/jm015509z

Reference yield:

: 15926-46-2
diethyl 2-phenyl-4,5-oxazoledicarboxylate

: 15926-44-0
2-phenyl-oxazole-4,5-dicarboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; at 40 ℃;
DOI:10.1248/cpb.15.627

Reference yield:

: 86555-45-5,714222-64-7
(2S)-N-benzoyl-L-aspartic acid dimethyl ester

: 15926-44-0
2-phenyl-oxazole-4,5-dicarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: LHMDS / tetrahydrofuran / -78 °C

1.2: 80 percent / iodine / tetrahydrofuran / -78 °C

2.1: benzene / Heating

2.2: 70 percent / NiO₂ / Heating

3.1: 93 percent / LiOH / tetrahydrofuran; H₂O / 20 °C

With lithium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; water; benzene;
DOI:10.1021/jm015509z