[carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride

Base Information

• Chemical Name: [carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride
• CAS No.: 882006-30-6
• Molecular Formula: C₁₁H₁₃N₂O₇*Cl
• Molecular Weight: 320.686

Synonyms:[carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride

Chemical Property of [carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride

Chemical Property:

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Technology Process of [carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride

There total 2 articles about [carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[ethoxycarbonylmethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid ethyl ester → [carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride (882006-30-6)

Guidance literature:

With hydrogenchloride; In water; at 50 ℃;

DOI:10.1081/SCC-200034816

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → [carboxymethyl-(2-hydroxy-5-nitro-benzyl)-amino]-acetic acid hydrochloride (882006-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / 16 h / 50 °C

2: 100 percent / hydrochloric acid / H₂O / 50 °C

With hydrogenchloride; In water; 1: Mannich aminomethylation;

DOI:10.1081/SCC-200034816

upstream raw materials:

4-nitro-phenol

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