(2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester

Base Information

• Chemical Name: (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester
• CAS No.: 259654-58-5
• Molecular Formula: C₂₁H₂₆OSe
• Molecular Weight: 373.397
• Mol file: 259654-58-5.mol

Synonyms:(2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester

Chemical Property of (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester

There total 4 articles about (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-phenylselanylphthalimide (71098-88-9) + (2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraenoic acid (29448-60-0,70143-08-7,70143-09-8,81680-53-7,81485-29-2) → (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester (259654-58-5)

Guidance literature:

With tributylphosphine; In dichloromethane; at -30 ℃;

DOI:10.1055/s-1999-2980

Reference yield:

ethyl (E)-3-formyl-2-butenoate (62054-49-3) → (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester (259654-58-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / n-BuLi / tetrahydrofuran / 20 °C

2: 73 percent / KOH; H₂O / methanol / Heating

3: 97 percent / Bu₃P / CH₂Cl₂ / -30 °C

With potassium hydroxide; n-butyllithium; tributylphosphine; water; In tetrahydrofuran; methanol; dichloromethane; 1: Condensation / 2: Hydrolysis / 3: Substitution;

DOI:10.1055/s-1999-2980

Reference yield:

ethyl (2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraenoate (29448-58-6,37384-80-8,51010-81-2,51010-78-7) → (2E,4E,6E)-3,7,11-Trimethyl-dodeca-2,4,6,10-tetraeneselenoic acid Se-phenyl ester (259654-58-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / KOH; H₂O / methanol / Heating

2: 97 percent / Bu₃P / CH₂Cl₂ / -30 °C

With potassium hydroxide; tributylphosphine; water; In methanol; dichloromethane; 1: Hydrolysis / 2: Substitution;

DOI:10.1055/s-1999-2980

upstream raw materials:

N-phenylselanylphthalimide

(2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraenoic acid

ethyl (E)-3-formyl-2-butenoate

ethyl (2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraenoate