4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate

Base Information

• Chemical Name: 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate
• CAS No.: 123715-62-8
• Molecular Formula: C₃₃H₄₀O₆S
• Molecular Weight: 564.743
• Mol file: 123715-62-8.mol

Synonyms:4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate

Chemical Property of 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate

There total 3 articles about 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

17β,19-dihydroxyadrost-4-en-3-one 17-benzoate 19-p-toluenesulfonate (79884-57-4) → 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate (123715-62-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; ethyl acetate; for 1h;

Reference yield:

17β,19-dihydroxy-androst-4-en-3-one 17-benzoate (20155-05-9) → 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate (123715-62-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / pyridine / 24 h / Ambient temperature

2: 85 percent / NaBH₄ / ethyl acetate; methanol / 1 h

With sodium tetrahydroborate; In pyridine; methanol; ethyl acetate;

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 4-androstene-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate (123715-62-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / pyridine / 24 h / Ambient temperature

2: 85 percent / NaBH₄ / ethyl acetate; methanol / 1 h

With sodium tetrahydroborate; In pyridine; methanol; ethyl acetate;

upstream raw materials:

17β,19-dihydroxyadrost-4-en-3-one 17-benzoate 19-p-toluenesulfonate

17β,19-dihydroxy-androst-4-en-3-one 17-benzoate

p-toluenesulfonyl chloride

Downstream raw materials:

4β,5-cyclopropano-5β-androstane-3β,17β,19-triol 17-benzoate 19-p-toluenesulfonate

4β,5-cyclopropano-5β-androstane-3β,17β,19-triol 3-acetate 17-benzoate 19-p-toluenesulfonate

Refernces