Gemcadiol

Base Information

• Chemical Name: Gemcadiol
• CAS No.: 35449-36-6
• Molecular Formula: C₁₄H₃₀O₂
• Molecular Weight: 230.391
• Hs Code.: 2905399090
• Mol file: 35449-36-6.mol

Synonyms:2,2,9,9-Tetramethyl-1,10-decanediol;CI 720; Gemcadiol; NSC 233811

Chemical Property of Gemcadiol

Chemical Property:

• Vapor Pressure: 2.81E-05mmHg at 25°C
• Melting Point: 61.5°C
• Refractive Index: 1.4705 (estimate)
• Boiling Point: 319.3°Cat760mmHg
• PKA: 14.93±0.10(Predicted)
• Flash Point: 136.7°C
• PSA: 40.46000
• Density: 0.904g/cm³
• LogP: 3.36400

Purity/Quality:

99% ^*data from raw suppliers

2,2,9,9-TETRAMETHYL-1,10-DECANEDIOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Antihyperlipoproteinemic.

Technology Process of Gemcadiol

There total 4 articles about Gemcadiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,9,9-tetramethyl-decanedioic acid (22092-62-2) → 2,2,9,9-Tetramethyl-1,10-decandiol (35449-36-6)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01145a050

Reference yield:

2,2,9,9-tetramethyl-decanedioic acid diamide (22092-67-7) → 2,2,9,9-Tetramethyl-1,10-decandiol (35449-36-6)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated sulfuric acid; aqueous sodium nitrite

2: lithium alanate; diethyl ether

With lithium aluminium tetrahydride; diethyl ether; sulfuric acid; sodium nitrite;

DOI:10.1021/ja01145a050

Reference yield:

2,2,9,9-tetramethyl-1,10-diphenyl-decane-1,10-dione (158300-02-8) → 2,2,9,9-Tetramethyl-1,10-decandiol (35449-36-6)

Guidance literature:

Multi-step reaction with 3 steps

1: toluene; sodium amide

2: concentrated sulfuric acid; aqueous sodium nitrite

3: lithium alanate; diethyl ether

With lithium aluminium tetrahydride; diethyl ether; sulfuric acid; sodium amide; toluene; sodium nitrite;

DOI:10.1021/ja01145a050

upstream raw materials:

2,2,9,9-tetramethyl-decanedioic acid

2,2,9,9-tetramethyl-decanedioic acid diamide

2,2,9,9-tetramethyl-1,10-diphenyl-decane-1,10-dione

Downstream raw materials:

2,2,9,9-tetramethyl-1,10-decanediol dinicotinate