22092-62-2Relevant academic research and scientific papers
Univalent and bivalent ligands of butorphan: Characteristics of the linking chain determine the affinity and potency of such opioid ligands
Decker, Michael,Fulton, Brian S.,Zhang, Bin,Knapp, Brian I.,Bidlack, Jean M.,Neumeyer, John L.
experimental part, p. 7389 - 7396 (2010/06/19)
Bivalent morphinan compounds containing ester linkers were synthesized and their binding affinities at the μ, δ, and κ opioid receptors determined. Addition of methyl groups adjacent to the hydrolytically labile ester linkage increased stability while onl
