6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

Base Information

Chemical Name:6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid
CAS No.:1031432-91-3
Molecular Formula:C₁₂H₁₂BF₃N₄O₃S
Molecular Weight:360.124
Hs Code.:
Mol file:1031432-91-3.mol

Synonyms:6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

Suppliers and Price of 6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

Chemical Property:

Purity/Quality:

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Technology Process of 6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

There total 9 articles about 6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1031432-65-1
N-{5-bromo-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-2-yl}-N′-ethylurea

: 73183-34-3
bis(pinacol)diborane

: 1031432-89-9
1-Ethyl-3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-2-yl)urea

: 1031432-93-5
N-ethyl-N'-{4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-2-yl}urea

: 1031432-91-3
6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 90 ℃; for 5h;

Reference yield:

: 1031432-65-1
N-{5-bromo-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-2-yl}-N′-ethylurea

: 73183-34-3
bis(pinacol)diborane

: 1031432-91-3
6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

Guidance literature:: N-{5-bromo-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-2-yl}-N′-ethylurea; bis(pinacol)diborane; With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 90 ℃; for 5h; Inert atmosphere; Microwave irradiation;

With hydrogenchloride; water; In dimethyl sulfoxide; at 100 ℃;

With sodium hydroxide; at 18 - 26 ℃; pH=5.5;