4-chloro-N-(3-chlorophenyl)benzamide

Base Information

• Chemical Name: 4-chloro-N-(3-chlorophenyl)benzamide
• CAS No.: 2447-96-3
• Molecular Formula: C₁₃H₉Cl₂NO
• Molecular Weight: 266.127
• NSC Number: 404960
• DSSTox Substance ID: DTXSID70323834
• Wikidata: Q82083089
• Mol file: 2447-96-3.mol

Synonyms:4-chloro-N-(3-chlorophenyl)benzamide;2447-96-3;Benzamide, 4-chloro-N-(3-chlorophenyl)-;Benzamide, N-(3-chlorophenyl)-4-chloro-;HMS1476M13;NSC404960;ChemDiv3_001333;CBDivE_001624;SCHEMBL4255341;DTXSID70323834;MFCD00444983;STK412525;AKOS001483908;NSC 404960;NSC-404960;IDI1_020299;NCGC00172767-01;AE-641/05499060;SR-01000418122;SR-01000418122-1

Chemical Property of 4-chloro-N-(3-chlorophenyl)benzamide

Chemical Property:

• Vapor Pressure: 0.000447mmHg at 25°C
• Boiling Point: 315.1°C at 760 mmHg
• Flash Point: 144.4°C
• PSA: 29.10000
• Density: 1.384g/cm³
• LogP: 4.31870
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 265.0061193
• Heavy Atom Count: 17
• Complexity: 264

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)Cl)NC(=O)C2=CC=C(C=C2)Cl

Technology Process of 4-chloro-N-(3-chlorophenyl)benzamide

There total 2 articles about 4-chloro-N-(3-chlorophenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-chlorophenyl)trimethylstannane (14064-15-4) + m-chlorophenyl isocyanate (2909-38-8) → 4-Chloro-N-(3-chlorophenyl)benzamide (2447-96-3)

Guidance literature:

With aluminium trichloride; Yield given. Multistep reaction; 1) CH₂Cl₂, 20 deg C, 15 min 2) 20 deg C, 2 h;

Reference yield:

→ 4-Chloro-N-(3-chlorophenyl)benzamide (2447-96-3)

Guidance literature:

4-Chlor-benzoesaeure-chlorid, 3-Chlor-anilin;

Reference yield:

4-Chloro-N-(3-chlorophenyl)benzamide (2447-96-3) + isopropyl chloroformate (108-23-6) → (4-Chloro-benzoyl)-(3-chloro-phenyl)-carbamic acid isopropyl ester (5892-89-7)

Guidance literature:

Multistep reaction; (i) NaH, (ii) /BRN= 506416/;

upstream raw materials:

(4-chlorophenyl)trimethylstannane

m-chlorophenyl isocyanate

Downstream raw materials:

(4-Chloro-benzoyl)-(3-chloro-phenyl)-carbamic acid isopropyl ester