Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

Base Information

Chemical Name:Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide
CAS No.:960078-49-3
Molecular Formula:C₄₆H₇₅N₃O₇
Molecular Weight:782.117
Hs Code.:

Synonyms:Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

Chemical Property:

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Technology Process of Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

There total 4 articles about Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 960078-47-1
Nω-(3,4,5-trioctyloxyphenyl)-L-phenylalaninamide

: 4530-20-5
BOC-glycine

: 960078-49-3
Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/chem.200700630

Reference yield:

: 960078-45-9
Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-L-phenylalaninamide

: 960078-49-3
Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

Guidance literature:: Multi-step reaction with 2 steps

1: TFA

2: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium*PF₆

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; trifluoroacetic acid;
DOI:10.1002/jms.1025

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 960078-49-3
Nα-(tert-butyloxycarbonyl)-Nω-(3,4,5-trioctyloxyphenyl)-glycyl-L-phenylalaninamide

Guidance literature:: Multi-step reaction with 3 steps

1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium*PF₆

2: TFA

3: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium*PF₆

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; trifluoroacetic acid;
DOI:10.1002/jms.1025