Technology Process of C44H62N2O2S
There total 3 articles about C44H62N2O2S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-tosyl tryptamine;
With
potassium tert-butylate;
In
1,4-dioxane;
at 20 ℃;
for 0.5h;
Inert atmosphere;
With
triethyl borane;
In
1,4-dioxane; hexane;
for 0.5h;
Inert atmosphere;
4-cholesten-3-bromide;
In
1,4-dioxane; hexane;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/ol4005992
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: cerium(III) chloride heptahydrate; sodium tetrahydroborate / tetrahydrofuran; methanol / 0.25 h / 0 °C
2.1: phosphorus tribromide / diethyl ether / 0.75 h / 0 °C / Inert atmosphere
3.1: potassium tert-butylate / 1,4-dioxane / 0.5 h / 20 °C / Inert atmosphere
3.2: 0.5 h / Inert atmosphere
3.3: 20 °C / Inert atmosphere
With
sodium tetrahydroborate; cerium(III) chloride heptahydrate; potassium tert-butylate; phosphorus tribromide;
In
tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether;
DOI:10.1021/ol4005992
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: phosphorus tribromide / diethyl ether / 0.75 h / 0 °C / Inert atmosphere
2.1: potassium tert-butylate / 1,4-dioxane / 0.5 h / 20 °C / Inert atmosphere
2.2: 0.5 h / Inert atmosphere
2.3: 20 °C / Inert atmosphere
With
potassium tert-butylate; phosphorus tribromide;
In
1,4-dioxane; diethyl ether;
DOI:10.1021/ol4005992
