Technology Process of (1R,2R,2'S,4E)-1-(N1,N2-dimethylglycinamide-2'-yl)-2-methyl-4-hexenyl benzoate
There total 5 articles about (1R,2R,2'S,4E)-1-(N1,N2-dimethylglycinamide-2'-yl)-2-methyl-4-hexenyl benzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 82 percent / (i-Pr)2NH, BuLi / tetrahydrofuran; hexane / 1.) -75 degC, 20 min; 2.) -100 degC, 50 min; 3.) 30 min, r.t.
2: 84 percent / 40 percent aq. NaOH / acetone / 12 h / 50 °C
3: 100 percent / 2 N HCl / ethanol / 4 h / 90 °C
With
hydrogenchloride; sodium hydroxide; n-butyllithium; diisopropylamine;
In
tetrahydrofuran; ethanol; hexane; acetone;
DOI:10.1002/hlca.19870700129
- Guidance literature:
-
Multi-step reaction with 4 steps
2: 82 percent / (i-Pr)2NH, BuLi / tetrahydrofuran; hexane / 1.) -75 degC, 20 min; 2.) -100 degC, 50 min; 3.) 30 min, r.t.
3: 84 percent / 40 percent aq. NaOH / acetone / 12 h / 50 °C
4: 100 percent / 2 N HCl / ethanol / 4 h / 90 °C
With
hydrogenchloride; sodium hydroxide; n-butyllithium; diisopropylamine;
In
tetrahydrofuran; ethanol; hexane; acetone;
DOI:10.1002/hlca.19870700129
