methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate

Base Information

• Chemical Name: methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate
• CAS No.: 1158806-27-9
• Molecular Formula: C₂₀H₂₇NO₁₂
• Molecular Weight: 474.426

Synonyms:methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate

Chemical Property of methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate

There total 2 articles about methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl [phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3-(S)-3-2H-3,5-dideoxy-2-thio-D-glycero-β-D-galacto-non-2-ulopyranoside]onate (1606160-13-7) → methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-2H-D-glycero-D-galacto-non-2-enonate (1158806-27-9) + methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate (73960-72-2)

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; In dichloromethane; at -40 ℃; Temperature; Overall yield = 71 %; stereoselective reaction; Molecular sieve;

DOI:10.1021/ol500917k

Reference yield:

methyl [phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3(R)-3-2H-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-non-2-ulopyranoside]onate (1606160-01-3) → methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-2H-D-glycero-D-galacto-non-2-enonate (1158806-27-9) + methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate (73960-72-2)

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; In dichloromethane; at 20 ℃; Temperature; Overall yield = 98 %; Molecular sieve;

DOI:10.1021/ol500917k

upstream raw materials:

methyl [phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3-(S)-3-²H-3,5-dideoxy-2-thio-D-glycero-β-D-galacto-non-2-ulopyranoside]onate

methyl [phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3(R)-3-²H-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-non-2-ulopyranoside]onate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1158806-27-9 methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-3-²H-D-glycero-D-galacto-non-2-enonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send