3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid

Base Information

• Chemical Name: 3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid
• CAS No.: 1182207-17-5
• Molecular Formula: C₂₂H₂₅N₅O₆
• Molecular Weight: 455.47
• Mol file: 1182207-17-5.mol

Synonyms:3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid

Chemical Property of 3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid

There total 1 articles about 3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

methyl 3-(N6-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoate (1182207-16-4) → 3-(N6-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid (1182207-17-5)

Guidance literature:

With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

DOI:10.1002/hlca.200900047

Reference yield:

3-(N6-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid (1182207-17-5) + chloroformic acid ethyl ester (541-41-3) → C23H24ClN5O7

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetone; at -10 ℃; Inert atmosphere;

DOI:10.1002/hlca.200900047

Reference yield:

3-(N6-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid (1182207-17-5) + chloroformic acid ethyl ester (541-41-3) → C22H24N8O5

Guidance literature:

3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoic acid; chloroformic acid ethyl ester; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetone; at -10 ℃; Inert atmosphere;

With sodium azide; In tetrahydrofuran; water; acetone; at -10 ℃; Inert atmosphere;

DOI:10.1002/hlca.200900047

upstream raw materials:

methyl 3-(N₆-[(benzyloxy)carbonyl]-9-{[(tert-butoxy)carbonyl]methyl}adenine-8-yl)propanoate