(R)-Glycidyl 1-naphthyl ether

Base Information

Chemical Name:(R)-Glycidyl 1-naphthyl ether
CAS No.:56715-28-7
Molecular Formula:C13H12 O2
Molecular Weight:200.237
Hs Code.:
European Community (EC) Number:611-416-2
UNII:QQ5S2IWE7E
DSSTox Substance ID:DTXSID30972165
Nikkaji Number:J475.260K
Wikidata:Q27287445

Synonyms:56715-28-7;(R)-Glycidyl 1-naphthyl ether;(R)-(-)-Glycidyl 1-naphthyl ether;Glycidyl 1-naphthyl ether, (R)-;CCRIS 6391;(2R)-2-(naphthalen-1-yloxymethyl)oxirane;R-(-)-ALPHA-NAPHTHYL GLYCIDYL ETHER;UNII-QQ5S2IWE7E;Oxirane, ((1-naphthalenyloxy)methyl)-, (R)-;QQ5S2IWE7E;(R)-((1-Naphthalenyloxy)methyl)oxirane;(R)-(-)-GLYCIDYL1-NAPHTHYLETHER;(2R)-2-[(1-Naphthalenyloxy)methyl]oxirane;SCHEMBL5026215;DTXSID30972165;(R)-(1-Naphthyloxymethyl)oxirane;R-(-)-?-Naphthyl Glycidyl Ether;MFCD01709480;AKOS030240715;AT28514;2-{[(Naphthalen-1-yl)oxy]methyl}oxirane;GLYCIDYL 1-NAPHTHYL ETHER, (-)-;LS-101087;(2R)-2-[(naphthalen-1-yloxy)methyl]oxirane;Oxirane,2-[(1-naphthalenyloxy)methyl]-,(2R)-;(R)-2-((NAPHTHALEN-1-YLOXY)METHYL)OXIRANE;Oxirane, 2-[(1-naphthalenyloxy)methyl]-, (2R)-;Q27287445

Suppliers and Price of (R)-Glycidyl 1-naphthyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
R-(-)-α-NaphthylGlycidylEther
250mg
$ 95.00

American Custom Chemicals Corporation
(R)-(-)-GLYCIDYL1-NAPHTHYL ETHER 95.00%
250MG
$ 319.20

Total 5 raw suppliers

Chemical Property of (R)-Glycidyl 1-naphthyl ether

Chemical Property:

PSA：21.76000
LogP:2.61740
Storage Temp.:-20?C Freezer
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:200.083729621
Heavy Atom Count:15
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

R-(-)-α-NaphthylGlycidylEther ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(O1)COC2=CC=CC3=CC=CC=C32
Isomeric SMILES:C1[C@@H](O1)COC2=CC=CC3=CC=CC=C32
Uses (R)-(-)-GLYCIDYL1-NAPHTHYLETHER used in the preparation of Naftopidil (N213500) enantiomers.

Technology Process of (R)-Glycidyl 1-naphthyl ether

There total 2 articles about (R)-Glycidyl 1-naphthyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2461-42-9
3-(1-naphthyloxy)-1,2-epoxypropane

: 62-53-3
aniline

: (R)-1-(naphthalen-1-yloxy)-3-(phenylamino)propan-2-ol

: C₁₉H₁₉NO₂

: 61249-00-1
(S)-(1-naphthyl) glycidyl ether

: 56715-28-7
(R)-1-(1-naphthyloxy)-2,3-epoxypropane

Guidance literature:: 3-(1-naphthyloxy)-1,2-epoxypropane; With C₆₅H₅₆CoN₃O₈; In dichloromethane; at 27 - 28 ℃; for 0.166667h;

aniline; In dichloromethane; at 27 - 28 ℃; enantioselective reaction;
DOI:10.1002/adsc.201700788

Reference yield:

: 2461-42-9
3-(1-naphthyloxy)-1,2-epoxypropane

: 36112-95-5
3-(1-naphthyloxy)propane-1,2-diol

: 56715-28-7
(R)-1-(1-naphthyloxy)-2,3-epoxypropane

Guidance literature:: 3-(1-naphthyloxy)-1,2-epoxypropane; With C₅₇H₅₄CoN₃O₈; In dichloromethane; at 20 ℃; for 0.25h;

With water; In dichloromethane; at 20 ℃; enantioselective reaction; Cooling with ice;
DOI:10.1002/adsc.201700788