[N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde

Base Information

• Chemical Name: [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde
• CAS No.: 1246677-42-8
• Molecular Formula: C₂₀H₁₇NO₃
• Molecular Weight: 319.36
• Mol file: 1246677-42-8.mol

Synonyms:[N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde

Chemical Property of [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde

There total 2 articles about [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

allyl bromide (106-95-6) + 2-(p-tolylamino)-3-formylchromone (445291-68-9) → [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde (1246677-42-8)

Guidance literature:

With potassium carbonate; sodium iodide; In acetonitrile; for 9h; Reflux;

DOI:10.1002/jhet.567

Reference yield:

C17H13NO3 (151112-74-2) → [N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde (1246677-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / Heating

2: potassium carbonate; sodium iodide / acetonitrile / 9 h / Reflux

With ethanol; potassium carbonate; sodium iodide; In acetonitrile;

DOI:10.1002/jhet.567

Reference yield: 80.0%

[N-(4-methylphenyl)-N-(prop-2-enyl)]amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde (1246677-42-8) + dimedone (126-81-8) → 11-allyl-6,11-dihydro-6-(5,5-dimethyl-3-hydroxy-2-cyclohexenone-2-yl)-8-methyl-1-benzopyrano[2,3-b]quinoline-5H-5-one (1246677-51-9)

Guidance literature:

With pyridine; In ethanol; for 5h; Reflux;

DOI:10.1016/j.tet.2010.07.028

upstream raw materials:

allyl bromide

2-(p-tolylamino)-3-formylchromone

C₁₇H₁₃NO₃

Downstream raw materials:

11-allyl-6,11-dihydro-6-(5,5-dimethyl-3-hydroxy-2-cyclohexenone-2-yl)-8-methyl-1-benzopyrano[2,3-b]quinoline-5H-5-one