8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline

Base Information

• Chemical Name: 8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline
• CAS No.: 945033-67-0
• Molecular Formula: C₂₅H₃₁BrN₂O₂Si
• Molecular Weight: 499.523
• Mol file: 945033-67-0.mol

Synonyms:8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline

Chemical Property of 8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline

There total 2 articles about 8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

(E/Z)-N-(2-nitrobenzylidene)-2-bromoaniline (17064-87-8) + allyl triisopropylsilane (24400-84-8) → 8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline (945033-67-0)

Guidance literature:

(E/Z)-N-(2-nitrobenzylidene)-2-bromoaniline; allyl triisopropylsilane; With bis(trifluoromethanesulfonyl)amide; In 1,2-dichloro-ethane; toluene; at 60 ℃; for 1h; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,2-dichloro-ethane; toluene; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jo8009243

Reference yield: 66.0%

C13H9BrN2O2 + allyl triisopropylsilane (24400-84-8) → 8-bromo-4-(triisopropylsilyl)methyl-2-(o-nitrophenyl)quinoline (945033-67-0)

Guidance literature:

C₁₃H₉BrN₂O₂; allyl triisopropylsilane; With triflic imide; In 1,2-dichloro-ethane; at 60 ℃; for 0.75h;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,2-dichloro-ethane; at 20 ℃; for 1h; Further stages.;

DOI:10.1016/j.tetlet.2007.05.032

upstream raw materials:

allyl triisopropylsilane

(E/Z)-N-(2-nitrobenzylidene)-2-bromoaniline