(1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine

Base Information

Chemical Name:(1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine
CAS No.:52758-03-9
Molecular Formula:C₁₇H₁₉N
Molecular Weight:237.345
Hs Code.:
UNII:X4CR040L3W
Nikkaji Number:J1.274.603B
Wikidata:Q27293547
Mol file:52758-03-9.mol

Synonyms:CP-22185;52758-03-9;(1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine;UNII-X4CR040L3W;X4CR040L3W;Sertraline hydrochloride specified impurity B [EP];1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, cis-(+/-)-;1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, (1R,4R)-rel-;SCHEMBL4619208;N-Methyl-4alpha-phenyltetralin-1alpha-amine;Q27293547;SERTRALINE HYDROCHLORIDE IMPURITY B [EP IMPURITY];(1R,4R)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine

Suppliers and Price of (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:237.151749610
Heavy Atom Count:18
Complexity:256

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1CCC(C2=CC=CC=C12)C3=CC=CC=C3
Isomeric SMILES:CN[C@@H]1CC[C@@H](C2=CC=CC=C12)C3=CC=CC=C3

Technology Process of (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine

There total 6 articles about (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52789-19-2
1-Methylimino-4-phenyl-1,2,3,4-tetrahydronaphthalin

: 52758-03-9,52758-04-0,52795-02-5,52795-04-7,54308-15-5,54308-16-6,62137-24-0,91797-61-4,91797-62-5
(+/-)-cis-1-Methylamino-4-phenyltetralin

Guidance literature:: With hydrogen; palladium on activated charcoal;
DOI:10.1021/jo00897a008

Reference yield:

: 52758-03-9,52758-04-0,52795-02-5,52795-04-7,54308-15-5,54308-16-6,62137-24-0,91797-61-4,91797-62-5
(+/-)-cis-1-Methylamino-4-phenyltetralin

Guidance literature:: N-Methyl-4-phenyl-1-tetralonimin, 1. NaBH4, 2. HCl-Gas od. DL-Mandelsaeure;

Reference yield:

: 52758-03-9,52758-04-0,52795-02-5,52795-04-7,54308-15-5,54308-16-6,62137-24-0,91797-61-4,91797-62-5
(+/-)-cis-1-Methylamino-4-phenyltetralin

: 52758-03-9,52758-04-0,52795-02-5,52795-04-7,54308-15-5,54308-16-6,62137-24-0,91797-61-4,91797-62-5
(+/-)-trans-1-Methylamino-4-phenyltetralin

Guidance literature:: Multi-step reaction with 3 steps

1: aq. KMnO₄

2: TiCl₄

3: Zn, AcOH

With potassium permanganate; titanium tetrachloride; acetic acid; zinc;
DOI:10.1021/jo00897a008