methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

Base Information

Chemical Name:methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate
CAS No.:189291-09-6
Molecular Formula:C₁₄H₁₉NO₄S
Molecular Weight:297.375
Hs Code.:

Synonyms:methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

Suppliers and Price of methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

There total 2 articles about methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 189291-08-5
methyl (2S,3R)-N-[(2,4,6-trimethylphenyl)sulfonyl]threoninate

: 189291-09-6
methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In chloroform; at 0 ℃; for 6h;
DOI:10.1021/jo962094u

Reference yield:

: 773-64-8
2-mesitylenesulphonyl chloride

: 189291-09-6
methyl (2S,3S)-3-methyl-N-[(2,4,6-trimethylphenyl)sulfonyl]-2-aziridinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) thionyl chloride, 2.) Et₃N / 1) -78 deg C, --> rt, 18 h; 2) DMF, CHCl₃, 0 deg C, 2 h

2: 81 percent / Ph₃P, diethyl azodicarboxylate / CHCl₃ / 6 h / 0 °C

With thionyl chloride; triethylamine; triphenylphosphine; diethylazodicarboxylate; In chloroform;
DOI:10.1021/jo962094u