Technology Process of C27H37NO4
There total 4 articles about C27H37NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C23H29NO4;
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
for 8h;
tert-butyl alcohol;
With
triethylamine;
In
dichloromethane;
at 20 ℃;
for 12h;
DOI:10.1016/j.bmcl.2012.08.104
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
2.1: palladium 10% on activated carbon; methanol / 20 °C
3.1: potassium carbonate / acetone / 6 h / Reflux
4.1: sodium hydroxide; water / methanol; tetrahydrofuran / 1 h / 20 °C / Cooling with ice
5.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 8 h / 20 °C
5.2: 12 h / 20 °C
With
methanol; oxalyl dichloride; palladium 10% on activated carbon; water; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1016/j.bmcl.2012.08.104
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: palladium 10% on activated carbon; methanol / 20 °C
2.1: potassium carbonate / acetone / 6 h / Reflux
3.1: sodium hydroxide; water / methanol; tetrahydrofuran / 1 h / 20 °C / Cooling with ice
4.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 8 h / 20 °C
4.2: 12 h / 20 °C
With
methanol; oxalyl dichloride; palladium 10% on activated carbon; water; potassium carbonate; N,N-dimethyl-formamide; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1016/j.bmcl.2012.08.104
