tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate

Base Information

• Chemical Name: tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate
• CAS No.: 780800-65-9
• Molecular Formula: C₁₆H₂₇N₃O₂
• Molecular Weight: 293.409
• Mol file: 780800-65-9.mol

Synonyms:tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate

Chemical Property of tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate

There total 2 articles about tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-methylpyridine-2-carboxaldehyde (55589-47-4) + 1-amino-4-[(tert-butyloxycarbonyl)amino]butane (68076-36-8) → tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate (780800-65-9)

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1021/acsmedchemlett.7b00381

Reference yield: 74.0%

3-methylpyridine-2-carboxaldehyde (55589-47-4) + tert-butyl (4-aminobutyl) carbamate → tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate (780800-65-9)

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 48h;

DOI:10.3390/molecules26206297

Reference yield: 85.0%

tert-butyl (4-(((3-methylpyridin-2-yl)methyl)amino)butyl)carbamate (780800-65-9) + 4-benzyl 1-(tert-butyl) 2-formylpiperazine-1,4-dicarboxylate → C34H51N5O6

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 1.5h;

upstream raw materials:

3-methylpyridine-2-carboxaldehyde

1-amino-4-[(tert-butyloxycarbonyl)amino]butane